Define epicgram; Regard not then if wit be old or new, But blame the false, and value still the true.?

the meaning of the epicgram.Define epicgram; Regard not then if wit be old or new, But blame the false, and value still the true.?
First, it's epigram. The one you cite means that it doesn't matter if knowledge/wisdom (the meaning of wit in the quote) is old or new, only if it is true or false. It referred to valuing new scientific discoveries over old religious beliefs (like a 6000 year old flat Earth with the Sun revolving around it).